Presentation of the Nurilia scientific team
Throughout my medical studies, I noticed the difficulty of treating infertile couples with conventional treatments.
Having been researcher at the national institute for medical research (Inserm) et obstetrician gynecologist specialized in medically assisted procreation, I opened myself up to wanting to seek complementary solutions to treatments. this is how our team was the first to explore the oxidation reduction of the DNA of infertile couples.
Following this research, we understood the vital importance of carrying out supplements aimed at protecting the DNA of gametes. we have therefore associated them with the treatments of our patients, and the results have been spectacular in many cases.
These formulas have also been the subject of studies that have been published for ten years in numerous French and international publications.
Interview with Dr. Marc Cohen
Dr. Cohen, what led you to seek an alternative solution?
This is related to my training which started at the National Institute of Health and Medical Research, where I carried out the theme of my doctoral thesis in medicine. Before setting up as a clinical gynecologist in a clinic in Lyon: I had the knowledge of a biochemist integrated with the knowledge of the clinician. The meeting of 2 French doctors who have worked in the United States: one in alternative medicine, the other, a biochemist at the National Institute for Agricultural Research (INRA) has made it possible to direct our research towards solutions that complement allopathic medicine.
The techniques of the time were mainly centered on organic causes of infertility and who little suspected the essential dimension of biochemistrye in fertility disorders.
The decisive impact that led to the creation of our concept was brought by the contribution of a group of gynecologists from Paris, integrated within the framework of a renowned Parisian laboratory, where the progress in this area, andt behind numerous international publications.
What have you discovered?
We have identified the problem of the aspect harmful to oxidative stress on fertility. The imbalance between cellular defense and the aggression of oxygenated free radicals is the cause of many failed pregnancy attempts.
At that time, we had already identified the negative role played by oxidative stress in sperm DNA fractures and in the disorganization of the nucleus of gametes in addition to the oxidation of membranes.
We have developed indices for measuring nuclear fragmentation and disorganization. This made it possible to assess the severity of male infertility and therefore to adapt the antioxidant treatment to the reduction of fragmentation and disorganization, a parameter that is completely independent of each other and does not raise it. of the same treatment. The last exploration which allowed us to solve a certain number of problems, which constituted a dead end, was operation of the MTHFR.
In addition, we were able to highlight the importance of enzymatic mutations as consequences of the action of oxidative stress (in particular of MTHFR), which is essential for the effectiveness of folic acid and its coenzymes.. The last element concerns the ability of reduced folic acid to recycle homocysteine, an essential condition for the stability of methylation, essential part of the reproductive system.
We have therefore developed the identification of MTHFR mutations and the use in our formulas of biologically active folic acid.
What do you advise?
First of all, don't hang around too much when you notice after six months (and not 2 years!) that regular intercourse does not lead to pregnancy.
Not to say that you have time, especially when you are 35 years old… knowing that endocrine disruptors, the nutritional or genetic deficit of group B, junk food, the environment etc… pose a problem!
It is therefore necessary to consult fertility specialists who must do, in addition to the classic examinations, the exploration of oxidative stress and the search for enzymatic mutations for men and women.